Abstract | OBJECTIVE: METHODS: Randomized, prospective, multicenter, open-label study. RESULTS: The total effective rate of levofloxacin was 90.8% (4103/4521). The effective rates of levofloxacin in the treatment of bacterial infections of respiratory tract, urinary tract, digestive tract and gynecologic infections and infections complicated with hematological disease were 90.2% (2884/3198), 92.3% (810/878), 91.9% (203/221), 94.5% (120/127), 88.7% (86/97), respectively. The bacterial eradication rate was 80.3% (677/843). The most common adverse drug reactions were gastrointestinal disorders (3.9%, 193/4888) and local irritation (1.7%, 84/4888), which were mild and disappeared after stopping administration. CONCLUSION:
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Authors | Cooperation Group for Phase IV Clinical Study of Levofloxacin |
Journal | Zhonghua nei ke za zhi
(Zhonghua Nei Ke Za Zhi)
Vol. 48
Issue 6
Pg. 492-6
(Jun 2009)
ISSN: 0578-1426 [Print] China |
PMID | 19954047
(Publication Type: Clinical Trial, Phase IV, English Abstract, Journal Article, Multicenter Study, Randomized Controlled Trial)
|
Chemical References |
- Anti-Bacterial Agents
- Levofloxacin
- Ofloxacin
|
Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
(therapeutic use)
- Bacterial Infections
(drug therapy)
- Female
- Humans
- Levofloxacin
- Male
- Middle Aged
- Ofloxacin
(therapeutic use)
- Prospective Studies
- Young Adult
|