[Report of the first case of influenza A (H1N1) in mainland China].

Abstract

OBJECTIVE:

To investigate the clinical characteristics and management of the first confirmed imported case of influenza A (H1N1) infection in mainland China.

METHODS:

The description of the clinical manifestations, clinical management, infection preventing and controlling strategies were reviewed.

RESULTS:

The 30-years old male patient came back from U.S.A. and with mild influenza-like symptoms developed. He had had a close contact history with a patient with "common cold" 4 d before onset of illness. Influenza A (H1N1) virus newly confirmed in North American was detected in the throat swab samples taken from this patient by real-time PCR and sequencing comparison. His symptoms ameliorated soon after administration of oseltamivir. The temperature was back to normal on the second day with oseltamivir. Nucleic acid of Influenza A (H1N1) virus was undetectable after 3 d with oseltamivir management. The patient was discharged on the 7 d after hospitalization.

CONCLUSIONS:

The clinical presentations of this imported case with Influenza A(H1N1) infection suggest that A(H1N1) infection manifests as flu-like symptoms in the healthy young people with a mild clinical course and a good prognosis. Early identification, early diagnosis and intervention with oseltamivir might be an effective clinical strategies for management of this emerging infectious disease.

• Authors: Hong Chen, Ya-ling Liu, Sheng-hua He, Yi-lan Zeng, Guang-fa Wang
• Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases (Zhonghua Jie He He Hu Xi Za Zhi) Vol. 32 Issue 7 Pg. 482-4 (Jul 2009) ISSN: 1001-0939 [Print] China
• PMID: 19953998 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antiviral Agents
• Oseltamivir

Topics

• Adult
• Antiviral Agents (therapeutic use)
• China (epidemiology)
• Humans
• Influenza A Virus, H1N1 Subtype
• Influenza, Human (diagnosis, drug therapy, epidemiology)
• Male
• Oseltamivir (therapeutic use)
• Prognosis