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Correlation between thickening of the inner and outer retina and visual acuity in patients with epiretinal membrane.

AbstractPURPOSE:
The purpose of this study was to examine the relationship between thickening of the inner and outer retinal layers and visual acuity in patients with idiopathic epiretinal membrane.
METHODS:
We examined 30 eyes of 30 patients and 25 eyes of 25 healthy volunteers as age-matched normal control subjects. The inner (between the vitreoretinal interface and the outer border of inner plexiform layer), outer, and full retinal thickness at the fovea, parafovea, and perifovea were measured using spectral-domain optical coherence tomography.
RESULTS:
Thickening ratios of both the inner and outer retina were greater in the fovea than in the other macular regions (P < 0.0001). Inner foveal retinal thickening was significantly greater than outer foveal retinal thickening (P < 0.0001). However, outer retinal thickening in the fovea (r = 0.644, P < 0.001), parafovea (r = 0.616, P < 0.001), and perifovea (r = 0.410, P = 0.025) was significantly correlated with visual acuity; inner retinal thickening was not. Visual acuity tended to be worse, although not significantly so, in eyes with photoreceptor disruption.
CONCLUSION:
Epiretinal membrane-induced retinal damage associated with visual acuity seems to be located within the outer retina external to the inner plexiform layer.
AuthorsShigeta Arichika, Masanori Hangai, Nagahisa Yoshimura
JournalRetina (Philadelphia, Pa.) (Retina) Vol. 30 Issue 3 Pg. 503-8 (Mar 2010) ISSN: 1539-2864 [Electronic] United States
PMID19952992 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Aged
  • Aged, 80 and over
  • Epiretinal Membrane (physiopathology)
  • Female
  • Fovea Centralis
  • Humans
  • Male
  • Middle Aged
  • Retina (pathology)
  • Tomography, Optical Coherence
  • Visual Acuity (physiology)

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