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No evidence for long-term effectiveness of early osteodistraction in hemifacial microsomia.

AbstractBACKGROUND:
The authors performed a critical literature review to find evidence of the long-term stability after early distraction osteogenesis of the mandible in patients with hemifacial microsomia.
METHODS:
The PubMed, Cochrane, MEDLINE, EMBASE, CENTRAL, and CINAHL databases were searched systematically for studies performed between 2002 and 2008. Abstracts from the 89 relevant articles were reviewed for evidence.
RESULTS:
Thirteen articles met the inclusion criteria. Data were tabulated with respect to the length of follow-up, number of patients, age group, Pruzansky-Kaban classification of the patients, methods of analysis and validation, and level of evidence. Methods for long-term follow-up studies were not standardized, and no objective studies have been published on stability after growth cessation.
CONCLUSIONS:
Thus far, no randomized controlled trials on early distraction osteogenesis in hemifacial microsomia patients have been published. The authors conclude that there is a lack of statistical evidence to support the use of early distraction osteogenesis for correcting hemifacial microsomia as a single treatment modality. The results call into question its rationale.
AuthorsKrisztián Nagy, Anne Marie Kuijpers-Jagtman, Maurice Y Mommaerts
JournalPlastic and reconstructive surgery (Plast Reconstr Surg) Vol. 124 Issue 6 Pg. 2061-2071 (Dec 2009) ISSN: 1529-4242 [Electronic] United States
PMID19952663 (Publication Type: Journal Article, Review)
Topics
  • Child, Preschool
  • Facial Asymmetry (congenital, diagnosis, surgery)
  • Facial Bones (abnormalities, surgery)
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mandible (abnormalities, surgery)
  • Osteogenesis, Distraction (adverse effects, methods)
  • Prospective Studies
  • Plastic Surgery Procedures (adverse effects, methods)
  • Retrospective Studies
  • Risk Assessment
  • Time Factors
  • Treatment Outcome

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