Abstract |
Aloe vera, as a biological vehicle for hydrocortisone 21-acetate, was tested topically and systemically against acute inflammation. Systemically, the combination of A. vera and hydrocortisone produced a maximum 88.1% inhibition of edema. Polymorphonuclear leukocyte infiltration was reduced 91.1%. The topical inhibition of edema peaked at 97%. The possibility that A. vera has significant potential as a biologically active vehicle for steroids is discussed.
|
Authors | R H Davis, W L Parker, D P Murdoch |
Journal | Journal of the American Podiatric Medical Association
(J Am Podiatr Med Assoc)
Vol. 81
Issue 1
Pg. 1-9
(Jan 1991)
ISSN: 8750-7315 [Print] United States |
PMID | 1993971
(Publication Type: Comparative Study, Journal Article)
|
Chemical References |
- Anti-Inflammatory Agents
- Pharmaceutical Vehicles
- hydrocortisone acetate
- Hydrocortisone
|
Topics |
- Acute Disease
- Administration, Topical
- Aloe
- Animals
- Anti-Inflammatory Agents
(administration & dosage, pharmacology)
- Female
- Hydrocortisone
(administration & dosage, analogs & derivatives, pharmacology)
- Inflammation
(drug therapy)
- Male
- Mice
- Pharmaceutical Vehicles
- Plants, Medicinal
- Rats
- Rats, Inbred Strains
|