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Aloe vera as a biologically active vehicle for hydrocortisone acetate.

Abstract
Aloe vera, as a biological vehicle for hydrocortisone 21-acetate, was tested topically and systemically against acute inflammation. Systemically, the combination of A. vera and hydrocortisone produced a maximum 88.1% inhibition of edema. Polymorphonuclear leukocyte infiltration was reduced 91.1%. The topical inhibition of edema peaked at 97%. The possibility that A. vera has significant potential as a biologically active vehicle for steroids is discussed.
AuthorsR H Davis, W L Parker, D P Murdoch
JournalJournal of the American Podiatric Medical Association (J Am Podiatr Med Assoc) Vol. 81 Issue 1 Pg. 1-9 (Jan 1991) ISSN: 8750-7315 [Print] United States
PMID1993971 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Anti-Inflammatory Agents
  • Pharmaceutical Vehicles
  • hydrocortisone acetate
  • Hydrocortisone
Topics
  • Acute Disease
  • Administration, Topical
  • Aloe
  • Animals
  • Anti-Inflammatory Agents (administration & dosage, pharmacology)
  • Female
  • Hydrocortisone (administration & dosage, analogs & derivatives, pharmacology)
  • Inflammation (drug therapy)
  • Male
  • Mice
  • Pharmaceutical Vehicles
  • Plants, Medicinal
  • Rats
  • Rats, Inbred Strains

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