Abstract |
A 45-year-old woman, with a body mass index of 41.8 kg/m2 and a medical history of anxiety-depression syndrome, had iatrogenic hypothyroidism and degenerative osteoarticular pathology of the spinal column and complained of a burning sensation behind the sternum associated with an acidic taste in her mouth. Symptoms had appeared 3 months previously and were especially prevalent when lying down, following large meals or after drinking coffee. The patient had started to experience symptoms on most days approximately 1 month earlier. Upper digestive endoscopy (UDE) revealed isolated erosions of the distal third of the oesophagus, compatible with a diagnosis of erosive reflux oesophagitis. Lifestyle changes were recommended and 8 weeks' treatment with pantoprazole 40 mg/day taken 15-30 minutes before breakfast was prescribed. Follow-up UDE showed resolution of oesophageal lesions with no pathological changes of the mucosa. Mild regurgitation and pyrosis persisted; therefore the patient continued to receive pantoprazole 40 mg for a further 3 weeks.
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Authors | Diana Brigas |
Journal | Clinical drug investigation
(Clin Drug Investig)
Vol. 29 Suppl 2
Pg. 17-8
( 2009)
ISSN: 1173-2563 [Print] New Zealand |
PMID | 19938882
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- 2-Pyridinylmethylsulfinylbenzimidazoles
- Anti-Ulcer Agents
- Pantoprazole
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Topics |
- 2-Pyridinylmethylsulfinylbenzimidazoles
(therapeutic use)
- Anti-Ulcer Agents
(therapeutic use)
- Esophagitis, Peptic
(complications, drug therapy, pathology)
- Female
- Gastroesophageal Reflux
(complications, drug therapy, pathology)
- Humans
- Middle Aged
- Obesity
(complications)
- Pantoprazole
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