Treatment of atypical central neurocytoma in a child with high dose chemotherapy and autologous stem cell rescue.

Abstract

The authors describe a 9 month old female with recurrent atypical central neurocytoma and leptomeningeal spread treated with high dose chemotherapy, autologous stem cell rescue, and adjuvant therapy. She had a complete response to therapy and was disease free at 4 years of age until a recurrence 6 months later. The use of intensive chemotherapy followed by autologous stem cell rescue for atypical neurocytoma may be considered as an adjunct to surgical therapy in young patients with atypical neurocytoma not amenable to radiation therapy.

• Authors: David Buchbinder, Moise Danielpour, William H Yong, Noriko Salamon, Joseph Lasky
• Journal: Journal of neuro-oncology (J Neurooncol) Vol. 97 Issue 3 Pg. 429-37 (May 2010) ISSN: 1573-7373 [Electronic] United States
• PMID: 19924515 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Brain Neoplasms (complications, drug therapy, surgery)
• Female
• Humans
• Infant
• Magnetic Resonance Imaging
• Meningeal Neoplasms (complications, drug therapy, surgery)
• Neurocytoma (complications, drug therapy, surgery)
• Tomography, X-Ray Computed (methods)