Abstract | OBJECTIVE: The objective of this study was to systematically review all the published articles examining the effects of low serum vitamin D concentration and vitamin D supplementation on muscle, balance and gait performance among people aged 65 and older. METHODS: RESULTS: Of the 102 selected studies, 16 met the selection criteria and were included in the final analysis. There were 8 observational studies and 8 interventional studies. The number of participants ranged from 24 to 33067. A majority of studies examined community-dwelling older women. Five observational studies showed a significant positive association, whereas three studies did not. Four of the 5 studies and two of the 3 studies which tested the vitamin D supplementation effect, respectively on balance and gait, showed no significant effect. Four studies showed a significant effect on muscle strength, while this effect was not observed in three others studies. In addition, there was no significant association between vitamin D supplementation and an improvement of the sit-to-stand test results in 50% of the studies. CONCLUSIONS: The findings show that the association between vitamin D and physical performance remains controversial. Observational studies and clinical trials yielded divergent results, which highlights the complex and to date still poorly understood association between serum vitamin D concentration or vitamin D supplementation and physical performance.
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Authors | C Annweiler, A M Schott, G Berrut, B Fantino, O Beauchet |
Journal | The journal of nutrition, health & aging
(J Nutr Health Aging)
Vol. 13
Issue 10
Pg. 893-8
(Dec 2009)
ISSN: 1760-4788 [Electronic] France |
PMID | 19924350
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Aging
(blood, physiology)
- Dietary Supplements
- Female
- Gait
(drug effects, physiology)
- Humans
- Male
- Muscle, Skeletal
(drug effects, physiology)
- Physical Fitness
- Postural Balance
(drug effects, physiology)
- Vitamin D
(administration & dosage, blood)
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