Abstract |
A 59-year-old man was diagnosed as having a pancreatic carcinoma with synchronous liver metastasis at initial surgery. After wedge resection of liver tumor for histopathological analysis and gastro- jejunostomy, he was treated with 3 cycles of combined systematic chemotherapy consisting of CDDP and CPT-11, because of histopathological diagnosis confirming a neuroendocrine carcinoma of the pancreas. After chemotherapy, there was no recurrence and the primary tumor was reduced in size. Therefore, pancreatico-duodenectomy was performed as a curative treatment in two stages. During the follow-up, the patient has been alive without any signs of recurrence for 20 months since the diagnosis. Recently, several consecutive chemotherapies have been an effective modality to improve a poor prognosis for unresectable neuroendocrine carcinoma.
|
Authors | Satoru Nomura, Akira Togawa, Takashi Kaiho, Kazuyasu Shinmura, Shinji Yanagisawa, Ryo Okamoto, Masaki Nishimura, Shun-ichi Tsuchiya, Masaru Miyazaki |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 36
Issue 11
Pg. 1897-900
(Nov 2009)
ISSN: 0385-0684 [Print] Japan |
PMID | 19920396
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Antineoplastic Agents
- Antineoplastic Agents, Phytogenic
- Irinotecan
- Cisplatin
- Camptothecin
|
Topics |
- Antineoplastic Agents
(administration & dosage)
- Antineoplastic Agents, Phytogenic
(administration & dosage)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Camptothecin
(administration & dosage, analogs & derivatives)
- Carcinoma, Neuroendocrine
(pathology, therapy)
- Cisplatin
(administration & dosage)
- Combined Modality Therapy
- Humans
- Irinotecan
- Liver Neoplasms
(secondary)
- Male
- Middle Aged
- Pancreatic Neoplasms
(pathology, therapy)
|