Relationship between iron-deficiency anemia and periodontal status in female patients.

Abstract

BACKGROUND:

The aim of this study was to evaluate the periodontal status of patients with iron-deficiency anemia (IDA) and the correlation of changes in serum and gingival crevicular fluid (GCF) ferritin levels after periodontal therapy.

METHODS:

Nineteen female patients with anemic hematologic values were classified as group A, and 20 healthy females with normal hematologic values were classified as group B. After group A was recruited, group B was enrolled with patients who had similar gingival indices as group A. At baseline and the 3-month follow-up visit, clinical periodontal indices and hematologic parameters were recorded, and GCF samples were taken. All patients received an oral hygiene-improvement session followed by scaling, and sites with >4-mm probing depths received root planing. At the 3-month follow-up visit, all measurements and analyses were repeated.

RESULTS:

During the follow-up period, all clinical indices decreased in both groups (P <0.05), but the gingival index in group A did not change. The GCF ferritin concentration showed statistically significant decreases (P <0.05), but total amounts of ferritin in GCF did not change. No significant correlation was found between serum and GCF ferritin levels.

CONCLUSION:

The findings of this study showed that changes in serum ferritin levels did not correlate with the GCF ferritin levels, and IDA was not a direct risk factor for periodontal diseases.

• Authors: Sukru Enhos, Ismet Duran, Sami Erdem, Sadik Buyukbas
• Journal: Journal of periodontology (J Periodontol) Vol. 80 Issue 11 Pg. 1750-5 (Nov 2009) ISSN: 1943-3670 [Electronic] United States
• PMID: 19905931 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Ferritins

Topics

• Adolescent
• Adult
• Anemia, Iron-Deficiency (blood, complications)
• Dental Plaque (therapy)
• Dental Plaque Index
• Dental Scaling
• Female
• Ferritins (analysis, blood)
• Follow-Up Studies
• Gingival Crevicular Fluid (chemistry)
• Humans
• Middle Aged
• Oral Hygiene
• Periodontal Attachment Loss (classification, therapy)
• Periodontal Diseases (classification, therapy)
• Periodontal Index
• Periodontal Pocket (classification, therapy)
• Root Planing
• Young Adult