High-dose methotrexate is effective in osteosarcoma so what is the problem?

Authors	Ian Joseph Cohen
Journal	Journal of pediatric hematology/oncology (J Pediatr Hematol Oncol) Vol. 31 Issue 12 Pg. 892-4 (Dec 2009) ISSN: 1536-3678 [Electronic] United States
PMID	19887958 (Publication Type: Comment, Journal Article)
Chemical References	Antimetabolites, Antineoplastic Methotrexate
Topics	Antimetabolites, Antineoplastic (administration & dosage) Bone Neoplasms (drug therapy) Humans Methotrexate (administration & dosage) Osteosarcoma (drug therapy) Treatment Outcome

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