HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Pars plana vitrectomy with ILM peeling for macular edema secondary to retinal vein occlusion.

AbstractPURPOSE:
To evaluate anatomic and functional results in patients with macular edema in retinal vein occlusion (RVO), treated with pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling, depending on the timing of surgery.
METHODS:
A total of 35 consecutive patients underwent PPV with ILM peeling. Visual acuity, fluorescein angiography, and optical coherence tomography/spectral optical coherence tomography were performed preoperatively and 6-12 months postoperatively.
RESULTS:
Anatomic improvement was achieved in 29 patients (82.9%). In 6 patients, there was no improvement. Central macular thickness decreased in 17 patients (48.6%) with central retinal vein occlusion (CRVO) and in 12 patients (34.3%) with branch retinal vein occlusion (BRVO) (p<0.05). A total of 68% of eyes showed improvement in visual acuity (p<0.05). Visual acuity improved in 14 patients (mean 3.7 Snellen lines) with CRVO and in 10 patients ( mean 3.7 Snellen lines) with BRVO. The t test shows no statistically significant difference in visual acuity improvement between ischemic and nonischemic CRVO (p>0.05) or between ischemic and nonischemic BRVO (p>0.05). Better results were observed in patients treated within 1 month of the onset of symptoms than in patients treated after more than 1 month. The difference is statistically significant (t test, p=0.0016).
CONCLUSIONS:
PPV with ILM peeling may improve anatomic and functional prognosis in patients with macular edema secondary to RVO. Vitrectomy with ILM peeling seems to be beneficial for macular edema secondary to RVO in patients treated within 1 month from the onset of symptoms. PPV with ILM peeling in ischemic RVO and nonischemic RVO improves visual acuity.
AuthorsMarzena Raszewska-Steglinska, Piotr Gozdek, Slawomir Cisiecki, Zofia Michalewska, Janusz Michalewski, Jerzy Nawrocki
JournalEuropean journal of ophthalmology (Eur J Ophthalmol) 2009 Nov-Dec Vol. 19 Issue 6 Pg. 1055-62 ISSN: 1120-6721 [Print] United States
PMID19882567 (Publication Type: Journal Article)
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Basement Membrane (surgery)
  • Female
  • Fluorescein Angiography
  • Humans
  • Macular Edema (etiology, physiopathology, surgery)
  • Male
  • Middle Aged
  • Prognosis
  • Prospective Studies
  • Retinal Vein Occlusion (complications, physiopathology, surgery)
  • Tomography, Optical Coherence
  • Visual Acuity (physiology)
  • Vitrectomy

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: