Conclusions. Anidulafungin is a new echinocandin developed for more effective treatment of serious systemic fungal infections.

Abstract

Anidulafungin is a new echinocandin developed for more effective treatment of serious systemic fungal infections. Anidulafungin is a well tolerated echinocandin with a favorable pharmacokinetic profile; in particular, its lack of hepatic metabolism and renal excretion enables drug administration without dosage adjustment to subjects with any degree of impaired hepatic or renal function. This simplifies dosing, with a requirement for only once-daily administration and a lack of drug-drug interactions in patients who require multiple medications.

• Authors: Pasquale De Bellis
• Journal: Drugs (Drugs) Vol. 69 Suppl 1 Pg. 99-102 ( 2009) ISSN: 1179-1950 [Electronic] New Zealand
• PMID: 19877742 (Publication Type: Journal Article)

Chemical References

• Antifungal Agents
• Echinocandins
• Anidulafungin

Topics

• AIDS-Related Opportunistic Infections (drug therapy, prevention & control)
• Anidulafungin
• Antifungal Agents (pharmacology, therapeutic use)
• Candidiasis (drug therapy, epidemiology, microbiology)
• Cross Infection (microbiology, prevention & control)
• Echinocandins (pharmacology, therapeutic use)
• Humans