Ultrastructural, electron-probe, and microhardness studies of the controversial amorphous areas in the dentin of regional odontodysplasia.

The amorphous areas, which are gray in sections stained with hematoxylin and eosin and which are a prominent feature in the coronal dentin of the more severely affected cases of regional odontodysplasia, were studied ultrastructurally and with an electron probe and a Vickers microhardnesss tester. The ultrastructural findings confirmed previous histochemical evidence that the amorphous material consists of glycosaminoglycans and represents collagen-free dentinal matrix, that is, ground substance. Phosphoproteins may also present. The ultrastructural examination of nondecalcified material and electron-probe and microhardness tests supported previous microradiographic evidence that the amorphous areas are more heavily mineralized than normal dentin. The boundaries of the amorphous areas were found on ultrastructural examination to be distinct but very irregular.
AuthorsD G Gardner, J P Sapp
JournalOral surgery, oral medicine, and oral pathology (Oral Surg Oral Med Oral Pathol) Vol. 44 Issue 4 Pg. 549-59 (Oct 1977) ISSN: 0030-4220 [Print] UNITED STATES
PMID198720 (Publication Type: Journal Article)
Chemical References
  • Glycosaminoglycans
  • Hydroxyapatites
  • Collagen
  • Child
  • Collagen
  • Dentin (analysis, ultrastructure)
  • Electron Probe Microanalysis
  • Female
  • Glycosaminoglycans
  • Hardness
  • Humans
  • Hydroxyapatites
  • Odontodysplasia (metabolism, pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: