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SUNCT syndrome successfully treated with the combination of oxcarbazepine and gabapentin.

Abstract
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is a syndrome of intermittent, brief, unilateral, severe paroxysms of orbital-temporal pain recurring multiple times per day. The pain modulation is often very difficult. The reported SUNCT patient is the first who responded to a combination treatment of oxcarbazepine and gabapentin.
AuthorsMartin Marziniak, Regina Breyer, Stefan Evers
JournalPain medicine (Malden, Mass.) (Pain Med) Vol. 10 Issue 8 Pg. 1497-500 (Nov 2009) ISSN: 1526-4637 [Electronic] England
PMID19863743 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Amines
  • Analgesics
  • Anticonvulsants
  • Cyclohexanecarboxylic Acids
  • oxcarbamazepine
  • Carbamazepine
  • gamma-Aminobutyric Acid
  • Gabapentin
Topics
  • Aged
  • Amines (administration & dosage)
  • Analgesics (administration & dosage)
  • Anticonvulsants (administration & dosage)
  • Carbamazepine (administration & dosage, analogs & derivatives)
  • Cyclohexanecarboxylic Acids (administration & dosage)
  • Drug Synergism
  • Drug Therapy, Combination
  • Gabapentin
  • Humans
  • Male
  • Orbit (innervation, physiopathology)
  • SUNCT Syndrome (drug therapy, physiopathology)
  • Thalamus (pathology, physiopathology)
  • Treatment Outcome
  • Trigeminal Nerve (drug effects, physiopathology)
  • Trigeminal Neuralgia (complications, physiopathology)
  • gamma-Aminobutyric Acid (administration & dosage)

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