Abstract |
This investigation studied triclosan retention and plaque viability in a group of healthy human subjects from Bangkok, Thailand, 12 hours after using a mouthrinse containing a triclosan/ PVM/MA copolymer system. The results show the retained triclosan in the dental plaque was with in or higher than the minimum inhibitory concentration (MIC range 0.27-6.25 microg/ml), indicating the triclosan in this product remains at an effective concentration in dental plaque. The 12-hour post-application evaluation demonstrated only 36.5% viability of oral bacteria in dental plaque after a one-time use of the mouthrinse. This study shows the benefits of using a mouthrinse containing a triclosan/ PVM/MA copolymer system for providing 12 hours long-lasting anti-bacteria and dental plaque control.
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Authors | Petcharat Kraivaphan, Cholticha Amornchat, Titikan Laothumthut, Terdphong Triratana |
Journal | The Southeast Asian journal of tropical medicine and public health
(Southeast Asian J Trop Med Public Health)
Vol. 40
Issue 4
Pg. 840-7
(Jul 2009)
ISSN: 0125-1562 [Print] Thailand |
PMID | 19842422
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Infective Agents, Local
- Benzoates
- Mouthwashes
- Plax
- Polymethacrylic Acids
- Polyvinyls
- poly(1-vinylimidazole-co-methyl methacrylate) copolymer
- Sodium Dodecyl Sulfate
- Triclosan
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Topics |
- Adolescent
- Adult
- Aged
- Anti-Infective Agents, Local
(pharmacokinetics)
- Benzoates
(pharmacokinetics)
- Dental Plaque
(drug therapy, microbiology)
- Double-Blind Method
- Female
- Humans
- Male
- Middle Aged
- Mouthwashes
(pharmacokinetics)
- Polymethacrylic Acids
(pharmacokinetics)
- Polyvinyls
(pharmacokinetics)
- Sodium Dodecyl Sulfate
(pharmacokinetics)
- Thailand
- Triclosan
(pharmacokinetics)
- Young Adult
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