Abstract | AIM: METHODS: From 1998 to 2008, a total of 133 newborns suffering from neonatal narcotic abstinence syndrome were treated at our clinic. All of these patients were born to mothers who had received methadone substitution for drug addiction during the course of pregnancy. RESULTS: CONCLUSION: This study suggests that a treatment of neonatal abstinence syndrome with clonidine in omission of opiates is possible without causing short-term adverse cardiovascular effects. Considering the retrospective design of the study, controlled and prospective trials are needed.
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Authors | A Esmaeili, A K Keinhorst, T Schuster, F Beske, R Schlösser, C Bastanier |
Journal | Acta paediatrica (Oslo, Norway : 1992)
(Acta Paediatr)
Vol. 99
Issue 2
Pg. 209-14
(Feb 2010)
ISSN: 1651-2227 [Electronic] Norway |
PMID | 19839963
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Hypnotics and Sedatives
- Chloral Hydrate
- Morphine
- Clonidine
- Methadone
- Phenobarbital
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Topics |
- Blood Pressure
(drug effects)
- Chloral Hydrate
(therapeutic use)
- Clonidine
(therapeutic use)
- Drug Therapy, Combination
- Female
- Humans
- Hypnotics and Sedatives
(therapeutic use)
- Infant, Newborn
- Length of Stay
(statistics & numerical data)
- Methadone
(adverse effects)
- Morphine
(therapeutic use)
- Neonatal Abstinence Syndrome
(drug therapy)
- Phenobarbital
(therapeutic use)
- Pregnancy
- Retrospective Studies
- Treatment Outcome
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