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A new concept in the topical treatment of onychomycosis with cyanoacrylate, undecylenic acid, and hydroquinone.

Abstract
The authors report a pilot study of a new approach for the topical treatment of onychomycosis using physiologic principles of fungal growth and serial debridement. In total, 154 patients were studied for 1 year with mild, moderate, and severe nail disease. Negative mycologic cultures in these 3 groups were 100%, 65%, and 35%, respectively. All patients reported subjective improvement in the first 3 months.
AuthorsPaul Rehder, Tim T Nguyen
JournalFoot & ankle specialist (Foot Ankle Spec) Vol. 1 Issue 2 Pg. 93-6 (Apr 2008) ISSN: 1938-7636 [Electronic] United States
PMID19825699 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antifungal Agents
  • Cyanoacrylates
  • Hydroquinones
  • Undecylenic Acids
  • hydroquinone
Topics
  • Administration, Topical
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antifungal Agents (administration & dosage)
  • Child
  • Cyanoacrylates (administration & dosage)
  • Debridement
  • Drug Therapy, Combination
  • Female
  • Foot Dermatoses (drug therapy)
  • Humans
  • Hydroquinones (administration & dosage)
  • Male
  • Middle Aged
  • Onychomycosis (drug therapy)
  • Treatment Outcome
  • Undecylenic Acids (administration & dosage)
  • Young Adult

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