[Management of serum calcium with cinacelet in parathyroid cancer].

Abstract

Treatment with cinacalcet and intravenous bisphosphonate has improved the previously often fatal prognosis of parathyroid cancer. We report two cases, of which one did not react to treatment and died within a short time-frame. In the other case, cinacalcet controlled serum calcium during a prolonged time period despite metastases. However, increasing doses of cinacalcet combined with more frequent intravenous bisphosphonate were necessary.

• Authors: Peter Vestergaard, Anne Katrine Sanden
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 171 Issue 41 Pg. 3004-6 (Oct 05 2009) ISSN: 1603-6824 [Electronic] Denmark
• Vernacular Title: Kontrol af serumcalcium med cinacalcet ved parathyroideacancer.
• PMID: 19814929 (Publication Type: Case Reports, Journal Article)

Chemical References

• Bone Density Conservation Agents
• Diphosphonates
• Imidazoles
• Naphthalenes
• Zoledronic Acid
• Calcium
• Cinacalcet

Topics

• Aged
• Bone Density Conservation Agents (administration & dosage, therapeutic use)
• Calcium (blood)
• Cinacalcet
• Diphosphonates (administration & dosage, therapeutic use)
• Fatal Outcome
• Female
• Humans
• Imidazoles (administration & dosage, therapeutic use)
• Male
• Naphthalenes (administration & dosage, therapeutic use)
• Parathyroid Neoplasms (blood, drug therapy)
• Prognosis
• Treatment Outcome
• Zoledronic Acid