[The features of immune status of major beta-thalassemia patients during various periods after splenectomy].

Abstract

The current researches were conducted to study humoral and cellular immunity in 118 major beta-thalassemia patients during various periods of time after splenectomy. Until the surgery the mentioned parameters of functional activities of segmented neutrophils in these patients were lower, since the second day, during a month after surgery the rates were gradually reducing, and during long date after splenectomy, these indices increased until baseline by the first year of the surgery and remained till the end of medical supervision. Thus, conducted researches showed that splenectomy renders oppressive influence upon the immune status of major beta-thalassemia patients, and all modified records of immunity recover and reach up to splenectomy level by the end of the first year after surgery.

• Authors: E A Kadymova
• Journal: Georgian medical news (Georgian Med News) Issue 174 Pg. 39-44 (Sep 2009) ISSN: 1512-0112 [Print] Georgia (Republic)
• PMID: 19801729 (Publication Type: English Abstract, Journal Article)

Chemical References

• Immunoglobulins

Topics

• Adolescent
• Child
• Child, Preschool
• Female
• Humans
• Immunoglobulins (blood)
• Lymphocytes (immunology)
• Male
• Neutrophils (immunology)
• Phagocytosis
• Postoperative Period
• Splenectomy
• beta-Thalassemia (blood, immunology, surgery)