The effectiveness of Proctofoam-HC for treatment of hemorrhoids in late pregnancy.

Abstract

OBJECTIVE:

Currently no topical anti-hemorrhoidal agents have been studied for effectiveness in pregnancy. This study evaluated the effectiveness of Proctofoam-HC used during the last trimester of pregnancy.

METHODS:

In this prospective, open-label, observational study, pregnant women prescribed Proctofoam-HC were asked to complete two telephone interview questionnaires.

RESULTS:

A total of 88 women completed the study. All hemorrhoidal symptoms, including pain, pruritus, swelling, itching, decreased significantly (P < 0.001) and overall well-being improved. The improvement was clinically very significant after correction for potential placebo effect.

CONCLUSIONS:

Proctofoam-HC appears to provide effective treatment of hemorrhoids in late pregnancy.

• Authors: Sabina Vohra, Hani Akoury, Paul Bernstein, Thomas R Einarson, Nicholas Pairaudeau, Anna Taddio, Gideon Koren
• Journal: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC (J Obstet Gynaecol Can) Vol. 31 Issue 7 Pg. 654-9 (Jul 2009) ISSN: 1701-2163 [Print] Netherlands
• PMID: 19761640 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents
• Drug Combinations
• Morpholines
• proctofoam-HC
• Hydrocortisone

Topics

• Administration, Topical
• Adult
• Anti-Inflammatory Agents (therapeutic use)
• Drug Combinations
• Female
• Hemorrhoids (drug therapy)
• Humans
• Hydrocortisone (therapeutic use)
• Morpholines (therapeutic use)
• Pregnancy
• Pregnancy Complications (drug therapy)
• Prospective Studies