[Effect of nutritional support on immune function in patients with severe pulmonary infection after renal transplantation].

Abstract

OBJECTIVE:

To study the effect of parenteral plus enteral nutrition (PN+EN) and total parenteral nutrition (TPN) support on the postoperative immune function in renal recipients with severe pulmonary infection.

METHODS:

Twenty renal recipients with severe postoperative pulmonary infection were randomly assigned into two equal groups to receive PN+EN or standard TPN, both supplied with equal nitrogen and calorie. The plasma levels of total protein, albumin, hemoglobin and peripheral blood IgA, IgG, IgM, total lymphocyte count, and CD4/CD8 ratio were measured before and after the treatment.

RESULTS:

The total lymphocyte count, CD4/CD8 ratio and IgG were significantly increased in patients receiving PN+EN as compared with those in TPN group (P<0.05). In both of the groups, the total protein and albumin levels underwent no significant changes after the nutritional support (P>0.05).

CONCLUSION:

PN+EN can better improve the immune function than TPN in renal recipients with severe pulmonary infection.

• Authors: Xue-Tao Cheng, Sheng-Ling Li, Guo-Lian Liu, Xiao-Ming Yang, Jun Lu
• Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University (Nan Fang Yi Ke Da Xue Xue Bao) Vol. 29 Issue 6 Pg. 1159-62 (Jun 2009) ISSN: 1673-4254 [Print] China
• PMID: 19726349 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Immunoglobulins

Topics

• Adult
• CD4-CD8 Ratio
• Enteral Nutrition
• Female
• Humans
• Immunoglobulins (blood)
• Kidney Transplantation
• Male
• Middle Aged
• Parenteral Nutrition
• Pneumonia (immunology, therapy)
• Postoperative Complications (immunology, therapy)