Abstract | INTRODUCTION: PATIENTS AND METHODS: A single-center cohort retrospective database analysis was performed of 497 consecutive adult patients who underwent first kidney transplantation between 1994 and 2004. At 1- and 5-year follow-up, a descriptive analysis was performed of mineral metabolism parameters of chronic kidney disease stage according to NKF KDOQI (National Kidney Foundation Kidney Disease Outcomes Quality Initiative) in patients with a functional graft at 1 year. Glomerular filtration rate was estimated using the abbreviated MDRD (Modification of Diet in Renal Disease) equation. RESULTS: Most of the transplants (99.2%) were from cadaveric donors. Mean (SD) patient age was 47.7 (13.3) years, and 69% of patients were men. The causes of chronic kidney disease were glomerular (35.4%), congenital (15.4%), systemic (14.1%), vascular (11.3%), interstitial (10.1%), and other (<1%). The percentage of patients in each stage of chronic kidney disease with calcium levels less than 8.5 mg/dL, phosphorus greater than 4.5 mg/dL, and PTHi greater than 150 pg/mL increased as graft function declined. Six posttransplantation parathyroidectomies were performed. Only 130 patients received secondary hyperparathyroidism treatment within 5 years after transplantation: calcium carbonate, 36.9%; calcium acetate, 1.5%; calcium carbonate plus cholecalciferol, 21%; calcitriol, 71%; and calcifediol, 0.8%. CONCLUSIONS:
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Authors | G Fernández-Fresnedo, E Rodrigo, J C Ruiz, A L Martín de Francisco, M Arias |
Journal | Transplantation proceedings
(Transplant Proc)
2009 Jul-Aug
Vol. 41
Issue 6
Pg. 2403-5
ISSN: 1873-2623 [Electronic] United States |
PMID | 19715933
(Publication Type: Journal Article)
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Topics |
- Adult
- Bone and Bones
(metabolism)
- Chronic Disease
- Cohort Studies
- Databases as Topic
- Female
- Follow-Up Studies
- Foundations
- Humans
- Kidney Diseases
(blood, classification, surgery)
- Kidney Failure, Chronic
(metabolism, surgery)
- Kidney Transplantation
(physiology)
- Male
- Middle Aged
- Postoperative Complications
(epidemiology)
- Retrospective Studies
- Time Factors
- Treatment Outcome
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