Abstract | BACKGROUND: RESULTS: Different altered stage correlative expression of the high abundance serum APPs was demonstrated in sera of the patients studied. While the expression of ACT, HAP and AAT appeared to demonstrate positive correlation with the three initial stages of the cancer, inverse correlation was apparently detected in the expression of LRG and CLU. For patients who were diagnosed with stage IV of the cancer, expression of the serum APPs did not conform to the altered progression changes. CONCLUSION: Our results highlight the potential prognostic significance of selective high abundance serum APPs in patients with EOCa.
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Authors | Yeng Chen, Boon-Kiong Lim, Onn H Hashim |
Journal | Journal of hematology & oncology
(J Hematol Oncol)
Vol. 2
Pg. 37
(Aug 27 2009)
ISSN: 1756-8722 [Electronic] England |
PMID | 19709441
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Acute-Phase Proteins
(analysis, metabolism)
- Adult
- Aged
- Carcinoma in Situ
(blood, diagnosis, metabolism, pathology)
- Case-Control Studies
- Electrophoresis, Gel, Two-Dimensional
- Female
- Humans
- Metabolome
- Middle Aged
- Neoplasm Staging
- Osmolar Concentration
- Ovarian Neoplasms
(blood, diagnosis, metabolism, pathology)
- Prognosis
- Young Adult
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