[Comparative assessment of efficacy of the 3d generation cephalosporins, ceftriabol, and claforan, in patients with community-acquired pneumonia].

Abstract

The aim of the study was to evaluate therapeutic efficiency of ceftriabol (Russia) and claforan (both 3d generation cefalosporins) used to manage severe extrahospital pneumonia. Ceftriabol (2 g) was administered one or twice daily, claforan intravenously (2 g b.i.d. or t.i.d). Results of the treatment were assessed from a combination of anamnestic and physical examination data, results of X-ray and laboratory studies. Normalization of major clinical, laboratory, and instrumental parameters in patients treated with ceftriabol and claforan was achieved roughly within the same time period. It means that ceftriabol is at least as efficacious as claforan when applied to the treatment of severe extrahospital pneumonia.

• Authors: Ia M Vakhrushev, O I Starodubtseva
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 87 Issue 7 Pg. 53-5 ( 2009) ISSN: 0023-2149 [Print] Russia (Federation)
• PMID: 19705794 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Ceftriaxone
• Cefotaxime

Topics

• Adult
• Aged
• Anti-Bacterial Agents (therapeutic use)
• Cefotaxime (therapeutic use)
• Ceftriaxone (therapeutic use)
• Community-Acquired Infections (drug therapy, physiopathology)
• Female
• Humans
• Male
• Middle Aged
• Pneumonia, Bacterial (drug therapy, physiopathology)
• Young Adult