Perioperative management of a child with von Willebrand disease undergoing surgical repair of craniosynostosis: looking at unusual targets.

Abstract

We report the successful management of a craniosynostosis repair in a child with severe Type I von Willebrand disease diagnosed during the preoperative assessment and treated by coagulation factor VIII and ristocetin cofactor. Collaboration among the anesthesiologist, the neurosurgeon, the clinical pathologist, and the pediatric hematologist is important for successful management.

• Authors: Isabelle Maquoi, Vincent Bonhomme, Jacques Daniel Born, Marie-Françoise Dresse, Elisabeth Ronge-Collard, Jean-Marc Minon, Pol Hans
• Journal: Anesthesia and analgesia (Anesth Analg) Vol. 109 Issue 3 Pg. 720-4 (Sep 2009) ISSN: 1526-7598 [Electronic] United States
• PMID: 19690238 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Adenosine Diphosphate
• Collagen
• Epinephrine

Topics

• Adenosine Diphosphate (metabolism)
• Anesthesiology (methods)
• Collagen (metabolism)
• Craniosynostoses (complications, surgery)
• Epinephrine (metabolism)
• Hemostasis
• Humans
• Infant
• Male
• Postoperative Period
• Surgical Procedures, Operative (methods)
• Treatment Outcome
• von Willebrand Diseases (complications, therapy)