Sulpiride-induced tardive dystonia.

Abstract

Sulpiride is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a 37-year-old man who developed persistent segmental dystonia within 2 months after starting sulpiride therapy. We could not find any previous reports of sulpiride-induced tardive dystonia.

• Authors: L G Miller, J Jankovic
• Journal: Movement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 5 Issue 1 Pg. 83-4 ( 1990) ISSN: 0885-3185 [Print] United States
• PMID: 1967484 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antipsychotic Agents
• Receptors, Dopamine
• Receptors, Dopamine D2
• Sulpiride

Topics

• Adult
• Antipsychotic Agents (adverse effects, therapeutic use)
• Dyskinesia, Drug-Induced (etiology)
• Dystonia (chemically induced)
• Humans
• Male
• Psychotic Disorders (drug therapy)
• Receptors, Dopamine (drug effects)
• Receptors, Dopamine D2
• Sulpiride (adverse effects, therapeutic use)