Adriamycin-induced cardiomyopathy aggravated by cis-platinum nephrotoxicity requiring dialysis.

Abstract

Complications of chemotherapy for a synovial sarcoma in an eight-year old boy included cisplatinum nephrotoxicity and adriamycin cardiotoxicity. The resultant renal failure and fluid overload necessitated peritoneal dialysis. Intractable hypomagnesemia was also a prominent feature.

• Authors: H N Tay, H K Yap, B Murugasu, T C Quah, S H Tay, J W Lim
• Journal: The Journal of the Singapore Paediatric Society (J Singapore Paediatr Soc) Vol. 32 Issue 3-4 Pg. 125-8 ( 1990) ISSN: 0037-5683 [Print] Singapore
• PMID: 1966850 (Publication Type: Case Reports, Journal Article)

Chemical References

• Doxorubicin
• Cisplatin

Topics

• Acute Kidney Injury (chemically induced, therapy)
• Cardiac Output, Low (chemically induced, therapy)
• Child
• Cisplatin (adverse effects, therapeutic use)
• Doxorubicin (adverse effects, therapeutic use)
• Femoral Neoplasms (drug therapy)
• Histiocytoma, Benign Fibrous (drug therapy)
• Humans
• Magnesium Deficiency (chemically induced, therapy)
• Male
• Peritoneal Dialysis