[Characteristics of synaptic structures of human brain in epilepsy and epileptic syndrome ].

The synaptoarchitectonics of different structural formations (cortex, hippocampus, amygdaloid complex) were assayed in 3 patients with epilepsia and 2 patients with associated temporal lobe glioma and epileptic syndrome using a selective technique of staining synapses with phosphotungstic acid and their morphometric study. It has been established that in the mechanism of brain epileptization, of paramount importance is the formation of new immature contacts, hypertrophy of functionally active synapses followed by their splitting and complication of the synaptic arrangement by the convergent and divergent type in the presence of derangement and death of a part of synapses. This is characteristic to a greater measure of the cortex from the area marked by regular epileptic activity and to a less measure of the hippocampus and amygdaloid complex.
AuthorsS I Ereniev, R I Genne, V V Semchenko, S S Stepanov
JournalZhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) (Zh Nevropatol Psikhiatr Im S S Korsakova) Vol. 90 Issue 10 Pg. 45-8 ( 1990) ISSN: 0044-4588 [Print] Russia (Federation)
Vernacular TitleOsobennosti sinaptoarkhitektoniki konechnogo mozga cheloveka pri épilepsii i épilepticheskom sindrome.
PMID1962997 (Publication Type: Comparative Study, English Abstract, Journal Article)
  • Adult
  • Amygdala (ultrastructure)
  • Epilepsy, Temporal Lobe (pathology)
  • Hippocampus (ultrastructure)
  • Humans
  • Microscopy, Electron
  • Synapses (ultrastructure)
  • Temporal Lobe (ultrastructure)

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