Abstract | BACKGROUND:
Granuloma annulare (GA) is a benign, usually self-limiting, dermatosis, that typically presents as asymptomatic, flesh-colored or erythematous papules, frequently arranged in an annular or arciform pattern on the distal extremities. Although localized GA is most commonly observed, a generalized or disseminated form can occur. The etiology of GA is unknown; however, multiple inciting factors have been proposed. Histologically, GA is characterized by foci of degenerative collagen associated with palisading, sometimes infiltrating granulomatous inflammation. OBSERVATIONS: CONCLUSION: Although our treatment was effective, further studies may be needed to confirm the success of this therapeutic option for patients with recalcitrant lesions of GA.
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Authors | Dione V Marcus, Bassel H Mahmoud, Iltefat H Hamzavi |
Journal | Archives of dermatology
(Arch Dermatol)
Vol. 145
Issue 7
Pg. 787-9
(Jul 2009)
ISSN: 1538-3652 [Electronic] United States |
PMID | 19620560
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Ofloxacin
- Minocycline
- Rifampin
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
(administration & dosage)
- Drug Therapy, Combination
- Female
- Granuloma Annulare
(drug therapy)
- Humans
- Male
- Middle Aged
- Minocycline
(administration & dosage)
- Ofloxacin
(administration & dosage)
- Rifampin
(administration & dosage)
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