Good syndrome accompanied by pure red cell aplasia.

Abstract

Thymomas are often associated with various autoimmune disorders. We herein report a middle-aged female patient with thymoma and hypogammaglobulinemia (Good syndrome) who developed symptomatic normocytic anemia. Her computed tomography (CT) scans showed a cervico-mediastinal mass. The findings of a bone marrow biopsy suggested pure red cell aplasia (PRCA), and the serum levels of all immunoglobulins were extremely low. After the resection of the tumor, which was diagnosed to be Masaoka stage II and type AB thymoma, the normocytic anemia dramatically improved, but the hypogammaglobulinemia did not recover.

• Authors: Tetsuo Taniguchi, Noriyasu Usami, Koji Kawaguchi, Kohei Yokoi
• Journal: Interactive cardiovascular and thoracic surgery (Interact Cardiovasc Thorac Surg) Vol. 9 Issue 4 Pg. 750-2 (Oct 2009) ISSN: 1569-9285 [Electronic] England
• PMID: 19608562 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adult
• Agammaglobulinemia (blood, diagnosis, immunology)
• Aged
• Biopsy
• Bone Marrow Examination
• Female
• Humans
• Male
• Middle Aged
• Neoplasm Staging
• Paraneoplastic Syndromes (blood, diagnosis, immunology)
• Red-Cell Aplasia, Pure (blood, diagnosis, immunology)
• Thymectomy
• Thymoma (blood, diagnosis, immunology, surgery)
• Thymus Neoplasms (blood, diagnosis, immunology, surgery)
• Tomography, X-Ray Computed
• Treatment Outcome