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Experimental approach to optimize phytate phosphorus utilization by broiler chickens by addition of supplements.

Abstract
Supplementation of 1alpha-hydroxycholecal-ciferol (1alpha-OHD(3)), phytase, and Ca levels has been shown to influence phytate P utilization. Two experiments were conducted with 1- to 16-d broilers to investigate the interactions between the effects of 1alpha-OHD(3), phytase, and Ca on phytate P utilization. In experiment 1, the birds were randomly allocated to 13 treatments with 6 levels of 1alpha-OHD(3) from 0 to 11microg/kg, with and without 500 U/kg of phytase supplemented to P-deficient diet. A positive control diet, adequate in Ca and P, was included. In experiment 2, a 3-dimensional rotatable design with 5 levels each of 1alpha-OHD(3), phytase, and Ca was implemented. Supplementation of 1alpha-OHD(3) and phytase increased phytate P utilization, as indicated by an increase in bone ash, phytate P disappearance, and BW. In experiment 1, no interaction between the 1alpha-OHD(3) and phytase effects was determined for any criteria, except for the incidence of P rickets. However, the second experiment showed that there were interactions between the 3 factors (1alpha-OHD(3), phytase, and Ca). The probabilities that observed variation in the 3-way interaction for measured criteria that were due to chance are: BW gain = 0.1364, G:F = 0.11, bone ash percentage = 0.0278, milligrams of bone ash/tibia = 0.0909, Ca rickets = 0.9394, P rickets = 0.4892, tibial dyschondroplasia = 0.5927, and phytate P disappearance = 0.1126. The equations obtained from the regression models were used to generate contour-surface plots. The percentage of bone ash data indicated that low Ca, high phytase, and high 1alpha-OHD(3) levels were needed to optimize phytate P utilization. The results of this study show that this experimental design may be utilized to identify the best levels of nutrients to add to a diet where complex 3-way interactions exist affecting several criteria. The equations may be used to optimize performance based on desired levels of performance and the costs of the inputs.
AuthorsA Liem, G M Pesti, A Atencio, H M Edwards Jr
JournalPoultry science (Poult Sci) Vol. 88 Issue 8 Pg. 1655-65 (Aug 2009) ISSN: 0032-5791 [Print] England
PMID19590081 (Publication Type: Journal Article, Randomized Controlled Trial)
Chemical References
  • Minerals
  • Phosphorus
  • bone ash
  • Phytic Acid
  • 6-Phytase
  • Calcitriol
  • Calcium
Topics
  • 6-Phytase (administration & dosage, pharmacology)
  • Animal Feed
  • Animal Nutritional Physiological Phenomena
  • Animals
  • Calcitriol (administration & dosage, pharmacology)
  • Calcium (pharmacology)
  • Chickens
  • Diet (veterinary)
  • Dietary Supplements
  • Dose-Response Relationship, Drug
  • Female
  • Male
  • Minerals (chemistry)
  • Phosphorus (metabolism)
  • Phytic Acid (metabolism)
  • Weight Gain (drug effects)

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