[Cavernous tissue rehabilitation whit sildenafil 100 mg in patients after radical prostatectomy].

Abstract

OBJECTIVES:

We try to figure out whether early penile rahabilitation ameliorates erectile dysfunction secondary to radical prostatectomy.

MATERIAL AND METHODS:

Retrospective study of 80 cases of patients that were operated between 2005-2008; all of them went under radical prostatectomy and were treated with sildenafil 100 mg every second day (Monday, Wednesday and Friday) plus 100 mg on demand after the surgery. As objective measurements, we used validated questionnaire IIEF-5 and also axil penile rigidity before and after surgery in the third and ninth month.

RESULTS:

Patients treated with sildenafil in fixed doses presented a 60% full erection recovery 9 months after radical prostatectomy. In the case where patients underwent bilateral or unilateral nerve sparing, they got a successful rate of almost 90%. Even 20% of those patients who did not have a nerve preservation got satisfactory erections,

CONCLUSIONS:

Our experience shows that early penile rehabilitation seems to be a good treatment for erectile dysfunction after radical prostatectomy with IPDE5 in fixed doses. Administration every other day plus on demand looks like also as an appropriate option.

• Authors: Manuel Fernández Arjona, Luis M Herranz Fernández, Pablo Garrido, Milagros Jiménez, Carlos Suárez, Inmaculada Fernández
• Journal: Actas urologicas espanolas (Actas Urol Esp) Vol. 33 Issue 4 Pg. 378-85 (Apr 2009) ISSN: 0210-4806 [Print] Spain
• Vernacular Title: Rehabilitación endotelial del tejido cavernoso con sildenafilo 100 mg en pacientes sometidos a prostatectomía radical.
• PMID: 19579888 (Publication Type: English Abstract, Journal Article)

Chemical References

• Phosphodiesterase Inhibitors
• Piperazines
• Purines
• Sulfones
• Sildenafil Citrate

Topics

• Aged
• Diagnostic Techniques, Urological (instrumentation)
• Equipment Design
• Erectile Dysfunction (diagnosis, drug therapy, etiology, rehabilitation)
• Humans
• Male
• Middle Aged
• Phosphodiesterase Inhibitors (administration & dosage)
• Piperazines (administration & dosage)
• Prostatectomy (adverse effects)
• Purines (administration & dosage)
• Retrospective Studies
• Sildenafil Citrate
• Sulfones (administration & dosage)