Abstract | OBJECTIVE: To explore the correlation between adipocyte factors ( adiponectin and visfatin) and fetus intrauterine growth. METHODS: RESULTS: (1) Serum visfatin levels in FGR mothers [(41.4 +/- 5.5)] microg/L were significantly higher than that in control women [(34.7 +/- 4.9) microg/L] and macrosomia mothers [(37.3 +/- 4.4) microg/L; P < 0.01, P < 0.05]. Serum adiponectin levels in macrosomia mothers [(4.1 +/- 1.3) mg/L] were significantly lower than that in control women [(6.6 +/- 1.5) mg/L] and FGR mothers [(6.4 +/- 1.3) mg/L; P < 0.01]. (2) Serum visfatin levels in FGR babies [(58.1 +/- 7.6) microg/L] were significantly increased than that in control newborns [(42.6 +/- 7.8) microg/L] and macrosomia babies [(48.5 +/- 9.1) microg/L; P < 0.01, P < 0.05]. Serum adiponectin levels in macrosomia babies [(6.5 +/- 1.3) mg/L] were significantly decreased than that in control newborns [(7.7 +/- 1.5) mg/L] and FGR babies [(7.7 +/- 1.0) mg/L; P < 0.05, P < 0.05]. (3) Maternal serum visfatin levels were positively correlated with umbilical serum visfatin levels (r = 0.720, P < 0.01). Umbilical serum adiponectin levels were higher than that in maternal serum, but there were no relationship between them (r = 0.301, P > 0.05). CONCLUSION:
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Authors | Li-xin Shang, Qing-ling Tang, Jing Wang, Fang Zhang, Nan Wu, Shu-he Wang, Ping Li |
Journal | Zhonghua fu chan ke za zhi
(Zhonghua Fu Chan Ke Za Zhi)
Vol. 44
Issue 4
Pg. 246-8
(Apr 2009)
ISSN: 0529-567X [Print] China |
PMID | 19570458
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Adiponectin
- Biomarkers
- Nicotinamide Phosphoribosyltransferase
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Topics |
- Adiponectin
(blood)
- Adult
- Biomarkers
(blood)
- Birth Weight
- Body Mass Index
- Enzyme-Linked Immunosorbent Assay
- Female
- Fetal Blood
(chemistry)
- Fetal Development
- Fetal Growth Retardation
(blood, physiopathology)
- Fetal Macrosomia
(blood, physiopathology)
- Humans
- Infant, Newborn
- Nicotinamide Phosphoribosyltransferase
(blood)
- Pregnancy
- Young Adult
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