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A fertile XY/XX chimeric male with chronic myeloid leukemia in a minor 46,XX cell line and a history of polycythemia vera and trisomy 9 in the major 46,XY cell line.

AuthorsKavita S Reddy, Gary Edward Schwartz, Mehdi Jamedhor
JournalLeukemia & lymphoma (Leuk Lymphoma) Vol. 50 Issue 8 Pg. 1375-80 (Aug 2009) ISSN: 1029-2403 [Electronic] United States
PMID19562617 (Publication Type: Case Reports, Letter)
Chemical References
  • Antineoplastic Agents
  • Benzamides
  • Piperazines
  • Pyrimidines
  • Imatinib Mesylate
  • Hydroxyurea
Topics
  • Aged
  • Antineoplastic Agents (therapeutic use)
  • Benzamides
  • Bone Marrow (pathology)
  • Chimera (embryology, genetics)
  • Chromosomes, Human, Pair 9
  • Chromosomes, Human, X
  • Chromosomes, Human, Y
  • Disease Progression
  • Fertility
  • Humans
  • Hydroxyurea (therapeutic use)
  • Imatinib Mesylate
  • In Situ Hybridization, Fluorescence
  • Incidental Findings
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive (complications, drug therapy, genetics, pathology)
  • Male
  • Neoplastic Stem Cells (ultrastructure)
  • Piperazines (therapeutic use)
  • Polycythemia Vera (complications, drug therapy, genetics, pathology)
  • Pyrimidines (therapeutic use)
  • Sex Chromosome Aberrations (embryology)
  • Trisomy (genetics)

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