Abstract | BACKGROUND: MATERIAL & METHODS: A retrospective study of all patients diagnosed with anorectal malformation in our institute from 1986-2008 was performed. All patients with anorectal malformation and Hirschsprung's disease were included in the study. Rectal biopsies were taken from multiple sites, including the rectum, left, transverse, right colon and appendix. The diagnosis of aganglionosis was proven histopathologically by the absence of ganglion cells with or without acetylcholinesterase staining. Specimens were examined by at least two experienced consultant pathologists. RESULTS: CONCLUSIONS: The association between ARM and intestinal dysganglionosis is not rare. We recommend not using the distal rectal pouch and parts of the fistula in the reconstruction of anorectal malformations as this may solve the constipation if the pathology is limited. In cases of aganglionosis beyond the rectal pouch and fistula, surgical intervention is needed. Delay in diagnosis may lead to morbidity or even mortality.
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Authors | E H Raboei |
Journal | European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie
(Eur J Pediatr Surg)
Vol. 19
Issue 5
Pg. 325-7
(Oct 2009)
ISSN: 1439-359X [Electronic] United States |
PMID | 19548194
(Publication Type: Case Reports, Journal Article)
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Copyright | (c) Georg Thieme Verlag KG Stuttgart - New York. |
Topics |
- Abnormalities, Multiple
(epidemiology, pathology)
- Anal Canal
(abnormalities)
- Anus, Imperforate
(epidemiology, pathology)
- Digestive System Abnormalities
(epidemiology, pathology)
- Down Syndrome
(epidemiology)
- Hirschsprung Disease
(epidemiology, pathology, surgery)
- Humans
- Infant, Newborn
- Male
- Rectum
(abnormalities)
- Retrospective Studies
- Saudi Arabia
(epidemiology)
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