Persistent superior oblique paresis as a manifestation of familial periodic cerebellar ataxia.

Abstract

A brother and sister complained of persistent diplopia due to superior oblique palsies. The cause of their symptoms became apparent when they were diagnosed as having familial periodic cerebellar ataxia (FPCA), a rare autosomal dominant condition. Oral acetazolamide (250 mg twice daily) not only prevented all the periodic symptoms but also relieved their diplopia, which had been present between attacks.

• Authors: P G Bain, G B Larkin, D M Calver, M D O'Brien
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 75 Issue 10 Pg. 619-21 (Oct 1991) ISSN: 0007-1161 [Print] England
• PMID: 1954213 (Publication Type: Case Reports, Journal Article)

Chemical References

• Acetazolamide

Topics

• Acetazolamide (therapeutic use)
• Adolescent
• Cerebellar Ataxia (complications, drug therapy, genetics)
• Diplopia (etiology)
• Female
• Humans
• Male
• Paralysis (etiology)