Abstract |
The aim of the study was to assess the influence of four mandibular protrusion positions, at a constant vertical dimension, on obstructive sleep apnea (OSA). Seventeen OSA patients (49.2 +/- 8.5 years) received an adjustable mandibular advancement device (MAD). The patients underwent four polysomnographic recordings with their MAD in situ at, in random order, 0%, 25%, 50%, and 75% of the maximum protrusion. The mean apnea-hypopnea index (AHI) values of the patients differed significantly between the protrusion positions (P < 0.000). The 25% protrusion position resulted in a significant reduction of the AHI with respect to the 0% position, while in the 50% and 75% positions, even lower AHI values were found. The number of side effects was larger starting at the 50% protrusion position. We therefore recommend coming to a weighted compromise between efficacy and side effects by starting a MAD treatment in the 50% protrusion position.
|
Authors | Ghizlane Aarab, Frank Lobbezoo, Hans L Hamburger, Machiel Naeije |
Journal | Clinical oral investigations
(Clin Oral Investig)
Vol. 14
Issue 3
Pg. 339-45
(Jun 2010)
ISSN: 1436-3771 [Electronic] Germany |
PMID | 19536571
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Adult
- Aged
- Body Mass Index
- Deglutition Disorders
(etiology)
- Facial Pain
(etiology)
- Female
- Follow-Up Studies
- Humans
- Male
- Mandibular Advancement
(instrumentation)
- Masseter Muscle
(physiopathology)
- Middle Aged
- Monitoring, Ambulatory
(instrumentation)
- Orthodontic Appliance Design
- Orthodontic Appliances
(adverse effects)
- Oxygen
(blood)
- Polysomnography
(instrumentation)
- Respiration
- Sleep Apnea, Obstructive
(therapy)
- Sleep Stages
(physiology)
- Snoring
(therapy)
- Supine Position
(physiology)
- Time Factors
- Tooth
(physiopathology)
- Vertical Dimension
|