Amnioinfusion for relief of recurrent severe and moderate variable decelerations in labor.

Abstract

OBJECTIVE:

To determine whether intrapartum amnioinfusion (AI) relieves recurrent moderate and severe variable decelerations in laboring women with clear or grade I meconium-stained amniotic fluid and reduces cesarean section rate for fetal distress.

STUDY DESIGN:

A randomized controlled trial was conducted in labor unit of Christian Medical College Hospital, Vellore, India, between October 2003 and September 2004. Women were randomized to receive AI (group I) and not to receive it (group II).

RESULTS:

A total of 150 women (75 in each group) were included in the study. There was significant relief of variable decelerations in group I and no difference in overall cesarean section rate but significant reduction in cesarean section rate for fetal distress in group I, and significant reduction in cesarean section rate for fetal distress in nulliparous women of group I. Neonatal acidemia was also significantly reduced in the nulliparous women receiving AI. The duration of maternal postpartum hospital stay was significantly reduced in group I. There were no adverse maternal or neonatal outcomes.

CONCLUSION:

AI was a beneficial therapeutic intervention in women patients showing fetal distress in first stage of labor, and it reduced cesarean section for fetal distress and neonatal acidemia.

• Authors: Annie Regi, Nancy Alexander, Ruby Jose, Jessie Lionel, Lilly Varghese, Abraham Peedicayil
• Journal: The Journal of reproductive medicine (J Reprod Med) Vol. 54 Issue 5 Pg. 295-302 (May 2009) ISSN: 0024-7758 [Print] United States
• PMID: 19517694 (Publication Type: Journal Article, Randomized Controlled Trial)

Topics

• Amniotic Fluid
• Cesarean Section (statistics & numerical data)
• Female
• Fetal Distress (therapy)
• Fetal Membranes, Premature Rupture (epidemiology)
• Heart Rate, Fetal
• Humans
• Infant, Newborn
• Infant, Newborn, Diseases (prevention & control)
• Labor, Obstetric
• Length of Stay
• Meconium
• Oligohydramnios (epidemiology)
• Parity
• Peroxisomal Disorders (prevention & control)
• Postpartum Period
• Pregnancy
• Recurrence