Treatment of acquired periodic alternating nystagmus with memantine: a case report.

We report a case of acquired periodic alternating nystagmus associated with common variable immunodeficiency and cutaneous sarcoid. The patient was initially treated with baclofen with minimal subjective improvement. We found a significant improvement in the patient's symptoms and nystagmus intensity after treatment with memantine.
AuthorsAnil Kumar, Shery Thomas, Rebecca McLean, Frank A Proudlock, Eryl Roberts, Mike Boggild, Irene Gottlob
JournalClinical neuropharmacology (Clin Neuropharmacol) 2009 Mar-Apr Vol. 32 Issue 2 Pg. 109-10 ISSN: 1537-162X [Electronic] United States
PMID19512963 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiparkinson Agents
  • Memantine
  • Antiparkinson Agents (pharmacology, therapeutic use)
  • Eye Movements (drug effects)
  • Humans
  • Male
  • Memantine (pharmacology, therapeutic use)
  • Middle Aged
  • Nystagmus, Pathologic (drug therapy, physiopathology)

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