Abstract | INTRODUCTION:
Seroma formation is one of the most common post operative complications related to abdominal wall hernia repairs with mesh. We hypothesized that the different biomaterials used to construct commonly used prosthetic mesh may influence permeability to fluid and affect seroma formation rates. METHODS: RESULTS: Each mesh was tested five times and the results averaged. The 3 meshes without anti-adhesive barriers (MM, PP, P) had fluid move across with minimal pressure (<1 mmHg). For the intraperitoneal mesh, there was a significant difference in pressure necessary for fluid movement (PR = 3.6, CQ = 36, PC = 56.6, DM > 350, BC > 350 mmHg, p = <0.001). However, the fenestrations at the suture lines necessary to combine the PP and DM in the BC mesh permitted fluid transport at low pressures (<1 mmHg). CONCLUSION: Based on our in vitro study, each mesh exhibited different fluid permeability, especially in the case of meshes with anti-adhesive barriers. This study also infers that methods to create pressure gradients across mesh, such as an abdominal binder, may reduce seroma formation of certain meshes.
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Authors | Judy Jin, Steve Schomisch, Michael J Rosen |
Journal | Surgical innovation
(Surg Innov)
Vol. 16
Issue 2
Pg. 129-33
(Jun 2009)
ISSN: 1553-3506 [Print] United States |
PMID | 19493920
(Publication Type: Journal Article)
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Topics |
- Adhesiveness
- Humans
- Hydrophobic and Hydrophilic Interactions
- Materials Testing
- Microfluidic Analytical Techniques
- Models, Biological
- Permeability
- Porosity
- Postoperative Complications
- Prosthesis Design
(adverse effects)
- Seroma
(etiology)
- Surgical Mesh
(adverse effects)
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