Recent advances in the treatment of acromegaly.

Abstract

PURPOSE OF REVIEW:

Description of recent outcomes and approaches to the treatment of patients with de-novo and recurrent acromegaly.

RECENT FINDINGS:

Radiosurgery for acromegaly results in a higher likelihood of remission and an earlier time to remission than does conventional radiotherapy. Somatostatin analogs results in control of acromegaly and one half of patients. Combining treatment with pegvisomant and somatostatin analogs results in overall improved quality of life.

SUMMARY:

Existing treatments offer patients and their treating physicians opportunities to restore life expectancy to normal and reverse many of the symptoms and signs of acromegaly.

• Authors: Manish Aghi, Lewis S Blevins Jr
• Journal: Current opinion in endocrinology, diabetes, and obesity (Curr Opin Endocrinol Diabetes Obes) Vol. 16 Issue 4 Pg. 304-7 (Aug 2009) ISSN: 1752-2978 [Electronic] England
• PMID: 19491667 (Publication Type: Journal Article, Review)

Chemical References

• Human Growth Hormone

Topics

• Acromegaly (drug therapy, surgery, therapy)
• Drug Therapy, Combination
• Human Growth Hormone (metabolism)
• Humans
• Life Expectancy
• Quality of Life