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Cemented total hip arthroplasty in a patient with alpha-mannosidosis: a case report.

Abstract
Mannosidosis is an extremely rare genetic disease occurring due to deficiency of the lysosomal enzyme, alpha-mannosidase. Patients with this disorder often suffer from musculoskeletal abnormalities and muscular weakness leading to joint destruction and severe morbidity along with other major systems involvement. We present here such a case of a 27-year-old male that highlights the challenges in management of hip joint destruction secondary to Mannosidosis.
AuthorsAravind S Desai, Asterios Dramis, Timothy N Board, Peter R Kay
JournalHip international : the journal of clinical and experimental research on hip pathology and therapy (Hip Int) 2009 Apr-Jun Vol. 19 Issue 2 Pg. 151-4 ISSN: 1724-6067 [Electronic] United States
PMID19462374 (Publication Type: Case Reports, Journal Article)
Topics
  • Adult
  • Arthroplasty, Replacement, Hip (adverse effects, instrumentation, methods)
  • Bone Plates
  • Hip Dislocation (etiology, surgery)
  • Humans
  • Joint Diseases (etiology, surgery)
  • Male
  • Reoperation
  • alpha-Mannosidosis (complications)

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