Abstract | BACKGROUND: OBJECTIVE: DESIGN: A crossover study was conducted in 12 patients with type 2 diabetes. Blood samples were collected over 8 h after ingestion of a test meal containing 100 g butter and 45 g carbohydrate in combination with 45 g casein (Cas-meal), whey (Whe-meal), cod (Cod-meal), or gluten (Glu-meal). We measured plasma concentrations of triglycerides, retinyl palmitate (RP), free fatty acids, insulin, glucose, glucagon, glucagon-like peptide 1, and glucose-dependent insulinotropic peptide. RESULTS: CONCLUSION: The data suggest that as a supplement to a fat-rich meal in patients with type 2 diabetes, whey protein seems to outperform other proteins in terms of postprandial lipemia improvement, possibly because of the formation of fewer chylomicrons or increased clearance of chylomicrons. The trial was registered at ClinicalTrials.gov as NCT00817973.
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Authors | Lene S Mortensen, Merete L Hartvigsen, Lea J Brader, Arne Astrup, Jürgen Schrezenmeir, Jens J Holst, Claus Thomsen, Kjeld Hermansen |
Journal | The American journal of clinical nutrition
(Am J Clin Nutr)
Vol. 90
Issue 1
Pg. 41-8
(Jul 2009)
ISSN: 1938-3207 [Electronic] United States |
PMID | 19458012
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Blood Glucose
- Caseins
- Dietary Fats
- Dietary Proteins
- Diterpenes
- Fatty Acids, Nonesterified
- Glycated Hemoglobin A
- Insulin
- Lipids
- Milk Proteins
- Retinyl Esters
- Triglycerides
- Whey Proteins
- Vitamin A
- retinol palmitate
- Glutens
- Glucagon
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Topics |
- Aged
- Animals
- Blood Glucose
(analysis)
- Caseins
- Cross-Over Studies
- Diabetes Mellitus, Type 2
(blood)
- Dietary Fats
- Dietary Proteins
(standards)
- Diterpenes
- Fatty Acids, Nonesterified
(blood)
- Female
- Fishes
- Glucagon
(blood)
- Glutens
- Glycated Hemoglobin
(analysis)
- Humans
- Insulin
(blood)
- Lipids
(blood)
- Male
- Meat
- Middle Aged
- Milk Proteins
(blood)
- Postprandial Period
(physiology)
- Retinyl Esters
- Triglycerides
(blood)
- Vitamin A
(analogs & derivatives, blood)
- Whey Proteins
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