Abstract |
Nearly all bacterial pathogens require iron to successfully infect their vertebrate hosts. The host molecule lipocalin-2 exploits this by sequestering bacterial siderophores as a mechanism of protection against infection. Raffatellu et al. (2009) show that Salmonella enterica serotype Typhimurium circumvents this through the production of the modified siderophore salmochelin.
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Authors | Eric P Skaar |
Journal | Cell host & microbe
(Cell Host Microbe)
Vol. 5
Issue 5
Pg. 422-4
(May 08 2009)
ISSN: 1934-6069 [Electronic] United States |
PMID | 19454345
(Publication Type: Comment, Journal Article)
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Chemical References |
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Topics |
- Enterocolitis
(immunology, microbiology)
- Host-Pathogen Interactions
- Humans
- Lipocalins
(immunology)
- Protein Binding
- Salmonella Infections
(immunology, microbiology)
- Salmonella typhimurium
(immunology)
- Siderophores
(immunology)
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