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A precious metal heist.

Abstract
Nearly all bacterial pathogens require iron to successfully infect their vertebrate hosts. The host molecule lipocalin-2 exploits this by sequestering bacterial siderophores as a mechanism of protection against infection. Raffatellu et al. (2009) show that Salmonella enterica serotype Typhimurium circumvents this through the production of the modified siderophore salmochelin.
AuthorsEric P Skaar
JournalCell host & microbe (Cell Host Microbe) Vol. 5 Issue 5 Pg. 422-4 (May 08 2009) ISSN: 1934-6069 [Electronic] United States
PMID19454345 (Publication Type: Comment, Journal Article)
Chemical References
  • Lipocalins
  • Siderophores
Topics
  • Enterocolitis (immunology, microbiology)
  • Host-Pathogen Interactions
  • Humans
  • Lipocalins (immunology)
  • Protein Binding
  • Salmonella Infections (immunology, microbiology)
  • Salmonella typhimurium (immunology)
  • Siderophores (immunology)

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