Abstract | PURPOSE: The aim of this study was to assess the clinical efficacy of combined treatment with local anesthetic and subanesthetic ketamine for the relief or prevention of postoperative pain, swelling, and trismus after the surgical extraction of third molars. PATIENTS AND METHODS: RESULTS: Facial swelling on postoperative days was significantly lower in the LAK group than in the LAA group (P = .0001). The mouth opening on the postoperative days was significantly greater in the LAK group than in the LAA group (P = .0001). The pain scores on the VAS at 30 minutes and 1, 4, 12, and 24 hours after surgery were significantly higher in the LAA group than in the LAK group (P = .0001, P = .005). CONCLUSION: The combination of a local anesthetic and subanesthetic doses of ketamine during surgical extraction of third molars can produce good local anesthesia while affording a comfortable procedure for the surgeon and patient and providing good postoperative analgesia with less swelling and significantly less trismus.
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Authors | Tülin Satilmiş, Hasan Garip, Esra Arpaci, Cem Sener, Kamil Göker |
Journal | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
(J Oral Maxillofac Surg)
Vol. 67
Issue 6
Pg. 1206-10
(Jun 2009)
ISSN: 1531-5053 [Electronic] United States |
PMID | 19446205
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Analgesics
- Anesthetics, Combined
- Anesthetics, Dissociative
- Anesthetics, Local
- Ketamine
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Topics |
- Adolescent
- Adult
- Analgesics
(administration & dosage)
- Anesthetics, Combined
(administration & dosage)
- Anesthetics, Dissociative
(administration & dosage)
- Anesthetics, Local
(administration & dosage)
- Edema
(prevention & control)
- Face
- Female
- Humans
- Ketamine
(administration & dosage)
- Male
- Mandible
(surgery)
- Molar, Third
(surgery)
- Pain Measurement
- Pain, Postoperative
(prevention & control)
- Postoperative Complications
(prevention & control)
- Time Factors
- Tooth Extraction
(adverse effects)
- Tooth, Impacted
(surgery)
- Trismus
(prevention & control)
- Young Adult
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