Abstract | PURPOSE OF REVIEW: Akathisa is one of the most common and distressing neuroleptic-induced extrapyramidal side effects. Although it is well recognized in the context of conventional antipsychotic medications, there have been recent concerns raised by clinicians and researchers that this syndrome is overlooked in relation to second-generation or atypical antipsychotics. This review examines the recent literature relevant to second-generation antipsychotic (SGA)-induced akathisia. RECENT FINDINGS: SUMMARY: Even though akathisia is less prevalent with SGAs than with the first-generation drugs, it remains clinically important and all clinicians should be conversant with its recognition and management.
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Authors | Rajeev Kumar, Perminder S Sachdev |
Journal | Current opinion in psychiatry
(Curr Opin Psychiatry)
Vol. 22
Issue 3
Pg. 293-99
(May 2009)
ISSN: 1473-6578 [Electronic] United States |
PMID | 19378382
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
- Antipsychotic Agents
- Dibenzothiazepines
- Isoxazoles
- Piperazines
- Piperidines
- Quinolones
- Thiazoles
- Benzodiazepines
- Quetiapine Fumarate
- ziprasidone
- Sulpiride
- Amisulpride
- Aripiprazole
- Clozapine
- Risperidone
- Olanzapine
- iloperidone
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Topics |
- Amisulpride
- Antipsychotic Agents
(adverse effects, therapeutic use)
- Aripiprazole
- Benzodiazepines
(adverse effects, therapeutic use)
- Clozapine
(adverse effects, therapeutic use)
- Dibenzothiazepines
(adverse effects, therapeutic use)
- Humans
- Isoxazoles
(adverse effects, therapeutic use)
- Olanzapine
- Piperazines
(adverse effects, therapeutic use)
- Piperidines
(adverse effects, therapeutic use)
- Prevalence
- Psychomotor Agitation
(epidemiology, etiology, physiopathology)
- Psychotic Disorders
(drug therapy)
- Quetiapine Fumarate
- Quinolones
(adverse effects, therapeutic use)
- Risk Factors
- Risperidone
(adverse effects, therapeutic use)
- Sulpiride
(adverse effects, analogs & derivatives, therapeutic use)
- Thiazoles
(adverse effects, therapeutic use)
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