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[Alcoholic ketoacidosis].

Abstract
Alcoholic ketoacidosis is an acute metabolic acidosis that typically occurs in people who chronically abuse alcohol and have a recent history of binge drinking, little or no food intake and persistent vomiting. Alcoholic ketoacidosis is a result of starvation with glycogen depletion and counter-regulatory hormone production, a raised nicotinamide adenine dinucleotide (NADH) to nicotinamide adenine dinucleotide (NAD+) ratio related to the metabolism of ethanol, and volume depletion resulting in ketogenesis. Alcoholic ketoacidosis is characterized by elevated serum ketone levels and a high anion gap. Once the diagnosis of alcoholic ketoacidosis is made, the mainstay of treatment is hydration with 5% dextrose in normal saline. With timely and aggressive intervention, the prognosis for a patient with alcoholic ketoacidosis is good.
AuthorsB Mihai, Cristina Lăcătuşu, Mariana Graur
JournalRevista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi (Rev Med Chir Soc Med Nat Iasi) 2008 Apr-Jun Vol. 112 Issue 2 Pg. 321-6 ISSN: 0048-7848 [Print] Romania
Vernacular TitleCetoacidoza alcoolică.
PMID19294998 (Publication Type: English Abstract, Journal Article, Review)
Chemical References
  • Sweetening Agents
  • Glucose
Topics
  • Alcoholic Intoxication (complications, diagnosis, therapy)
  • Diagnosis, Differential
  • Fluid Therapy (methods)
  • Glucose (therapeutic use)
  • Humans
  • Ketosis (diagnosis, etiology, therapy)
  • Prognosis
  • Sweetening Agents (therapeutic use)
  • Treatment Outcome

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