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Disseminated cerebral histiocytosis X responding to vinblastine therapy: a case report.

Abstract
A case of intracranial histiocytosis X with multiple parenchymal brain lesions is described. Despite severe neuroradiological findings, and involvement of a node and vertebra on presentation, the child is doing well clinically, with outpatient chemotherapy, 36 months after diagnosis. The prognosis of cerebral involvement in such atypical cases should probably be reevaluated. Therapeutic problems are discussed.
AuthorsM A Carpentier, J Maheut, M C Grangeponte, C Billard, J J Santini
JournalBrain & development (Brain Dev) Vol. 13 Issue 3 Pg. 193-5 (May 1991) ISSN: 0387-7604 [Print] Netherlands
PMID1928614 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Vinblastine
  • Prednisone
Topics
  • Brain Neoplasms (diagnostic imaging, drug therapy, pathology)
  • Female
  • Histiocytosis, Langerhans-Cell (diagnostic imaging, drug therapy, pathology)
  • Humans
  • Infant
  • Lymph Nodes (pathology)
  • Prednisone (therapeutic use)
  • Tomography, X-Ray Computed
  • Vinblastine (therapeutic use)

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