Insights from experimental data on ciprofloxacin in the treatment of bacterial keratitis and ocular infections.

Abstract

Ciprofloxacin is a potent fluoroquinolone antibiotic with in vitro activity against many significant gram-positive and gram-negative ocular pathogens. A review of the experimental studies of this antibiotic shows bactericidal activity, a broad antimicrobial spectrum, and a low incidence of resistance. The growing body of experimental data supports the effectiveness of ciprofloxacin in the treatment of experimental keratitis and suggest that it be evaluated further in ocular infections.

• Authors: C D Cokingtin, R A Hyndiuk
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 112 Issue 4 Suppl Pg. 25S-28S (Oct 1991) ISSN: 0002-9394 [Print] United States
• PMID: 1928270 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Review)

Chemical References

• Ciprofloxacin

Topics

• Bacterial Infections (drug therapy)
• Ciprofloxacin (pharmacokinetics, therapeutic use)
• Drug Resistance, Microbial
• Eye Diseases (drug therapy, microbiology)
• Humans
• Keratitis (drug therapy, microbiology)
• Pseudomonas Infections (drug therapy)